Ultra-low permeability reservoir in Ordos Basin has large oil resource, but it has poor physical properties and high starting pressure gradient, so it is hard to be exploited. According to these characteristics, the development strategies of “advanced water injection, well space shortening, rising injection-to-production-well ratio, increasing artificial fracture length and fluid diversion capacity”are proposed, and good result has been achieved in the pilot tracey in Zhuang 9 wellblock, Xifeng Oilfield. The development design settles a strong base for the efficient development of ultra-lowpermeability reservoir and broadens the prospects of oil and gas exploration and development in Ordos Basin.