The block D of Cambodia Sea in Gulf of Thailand is a newarea with low exploration degree. The petroleum geology study on the nearing area is much deeper. However, there has no systematic sequence division in the block Dby now. The 2D seismic lines played a main part together with the assist of the nearingwell. The sequence divisions inwell and seismic sections are carried out individually. Combined with the two divisions, the comprehensive sequence division of the area is obtained. There are totally 6 sequences, and the first isochronal sequence framework is set up. In the unit of sequence, the section feature and plane feature of the seismic facies are analyzed. The method used here offers an effective way for the study of sequence stratigraphy on offshore low-degree exploration areas.