Tight and lowpermeability reservoirs have obvious stress-sensitivity phenomenon. The relationship between permeability ratio and effective stress is established by the stress-sensitivity experiment of core and the research on the rules of core permeability changing with effective stress. Effective permeability reduces with the increasing of effective pressure .The inconvertible permeability damages reach to 0.55％～24％ and the average is 8.1％.The pressure equation considering stress-sensitivity of gas well can be given by the influence of stress-sensitivity on abandonment pressure. And then the influence of stress-sensitivity on recovery ratio are studied referring to a simple equation compution of recovery ratio.