Loggingmethod can be used to continuouslymeasure the rock mechanics characteristics, but when used to calculate stress, the data error is large. The mechanical characteristics measured by core testing are accurate, however, the amount of the core testing is little. The fracturing testing technique is taken as the best method to directional survey the in-situ stress, but due to the conditions, it is seldom applied which restricts this method to calculate continuous stress profile. The triaxial stress experiment in high temperature and high pressure is carried out to test the rock static mechanical behavior, and logging data are used to calculate the rock dynamic mechanical behavior. The relation of the static and dynamic parameters is established, and then the static rock mechanical characteristics in longitudinal can be obtained. Combined with the layered stress profile model from the fractured testing, the in-situ stress profile can be obtained. The layered stress profile model is established in XX block in Erlian Basin, and the calculated result coincides with the actual measurement，so using the method to predict the in-situ stress profile is feasible, which provides effective parameters for the further development.