In order to study oil and gas accumulation law of Ed1 in Nanpu Depression, the main controlling factors and models of Ed1 in Nanpu Depression were studied by research method of reservoir anatomy and matching relation between hydrocarbon distribution and accumulation conditions. The result shows that oil and gas accumulation and distribution are controlled by following four factors: （1） faults connected with source rocks are main transporting pathways for oil and gas migratingverticallytoEd1; （2） the place where oil and gas migrate through Ed2 mudstone cap rocks, but sealed by Ng Ⅲ volcanic cap rocks is favorable for oil and gas migratingintoEd1; （3） the places where the ratio between sandstone and stratum is more than 20% are favorable for oil and gas migrating laterally into Ed1; （4） positive structures near faults connected with source rocks are favorable place for oil and gas to accumulate. Oil and gas accumulation models of Ed1 are that oil and gas from underlying Es3 or Es1-Ed3 source rocks migrate along faults connected with source rocks intoEd1 in the places where oil and gas migrate through Ed2 mudstone cap rocks but sealed by Ng Ⅲ volcanic cap rocks, oil and gas migrate laterally into strata of Ed1 with the ratio between sandstone and stratum being more than 20%, accumulate in fault block, fault sealing and fault-lithology traps on positive structures near faults connected with source rocks and form oil and gas reservoirs.