After forty-three years ofwaterflood development of the reservoirs in Xing 6 district, it is nowin high water cut stage of development, and the water absorption of reservoirs is seriously uneven. Compared with conventional injection profile, Lohrentz curve is used to study that the uneven extent of injection profile of twowells in Xing 6 district is caused by reservoir heterogeneity and human factors, and analyze the differences of injection profiles before and after adjustment and the differences of injection profile in different times. Based on the analysis of Gini Coefficient in Lohrentz curve, “nonuniformity coefficient” was introduced to measure water absorption of different layers and the uneven extent of injection profile. It is considered that the uneven extent of injection profile in Xing 6 reservoirs is becoming more and more serious. Meanwhile, some corresponding adjustment measures were offered. All these provide a foundation for the further development and relevantmeasure adjustment in this oilfield.