The DX 12 well field is characterized by relatively small sand bodies, low reserves abundance and has the characteristic of “one sand, one reservoir”. The method of scattered water flooding is applied to develop the nonoverlapping regions of the reservoir. This paper established a reservoir physical simulation system of five-spot water flooding pattern, verified the effectiveness and practicality about vector well pattern in the development of heterogeneous reservoir, and applied the theory of vector well pattern combined with the method of numerical simulation to optimize the scattered well pattern of non-overlapping regions of the small reservoir in DX 12 well field. The result shows that the optimization of well pattern has a significant effect on improving the development effect and enhancing the producible oil index.