Based on geologic characteristics of Kexia heavy oil reservoir, research on shrink-proof expansion treatment was carried out before huff and puff test. Combined with the results of reservoir sensitivity evaluation, shrink-proof expansion optimization and static performance evaluation, through the research of temperature resistance performance and core flow experiments, this paper determined the anti-swelling cycles, treatment radius and injection program on site. The results show that the favorable anti-swelling agents are 1% HCS-G and 1% EXHCS, they are resistant to high temperature of 230 ℃, and can meet the requirements of steam stimulation; The shrink-proof treatment radius is 3.5 m, the anti-swelling cycle is about 2 years, and shrinkage and expansion cycle is about 1 year. And this paper also designed the injection program on site.