The Banghu Syncline in Qianjiang Sag with abundant oil and gas resources is a typical inland lake by salt deposit. It is the favorable area for lithologic reservoir exploration. Because of complex vertical lithology combination, quickly lateral change of sand bodies, impedance of reservoir and non reservoir laminated obviously, it is difficult to identify the reservoir just by seismic attribute analysis and post-stack acoustic impedance inversion. Through many years of research, this paper put forward facies controlled reservoir prediction technology with high-fidelity pre-stack migration seismic data as a foundation, and the pre-stack simultaneous inversion of density as the core, and discussed the key technologies in pre-stack simultaneous inversion of density such as shear wave velocity estimation, stacked angels division and fluid detection. Practice proved that these exploration techniques are feasible, and they could be effectively used to identify lithologic traps and have great application prospects.